Source:http://linkedlifedata.com/resource/pubmed/id/20946119
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-10-27
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pubmed:abstractText |
Fab fragments (Fabs) of antibodies maintain the ability to bind specific antigens, but lack the binding site for complement as well as the site for binding to receptors on effector cells, such as macrophages that play an important role in inflammation. In the present study, we investigated whether Fabs specific for ovalbumin (OVA) were specifically able to suppress anti-OVA antibody-mediated arthritis (AOA-MA) in mice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1476-5381
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pubmed:author | |
pubmed:copyrightInfo |
© 2010 The Authors. British Journal of Pharmacology © 2010 The British Pharmacological Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1351-60
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pubmed:dateRevised |
2011-11-1
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pubmed:meshHeading |
pubmed-meshheading:20946119-Animals,
pubmed-meshheading:20946119-Antibodies,
pubmed-meshheading:20946119-Antigen-Antibody Reactions,
pubmed-meshheading:20946119-Arthritis, Experimental,
pubmed-meshheading:20946119-Immunoglobulin Fab Fragments,
pubmed-meshheading:20946119-Male,
pubmed-meshheading:20946119-Mice,
pubmed-meshheading:20946119-Mice, Inbred DBA,
pubmed-meshheading:20946119-Ovalbumin
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pubmed:year |
2010
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pubmed:articleTitle |
Suppression of antibody-mediated arthritis in mice by Fab fragments of the mediating antibodies.
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pubmed:affiliation |
Department of Pharmacology, Kobe Pharmaceutical University, Kobe, Japan. yoshino@kobepharma-u.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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