Source:http://linkedlifedata.com/resource/pubmed/id/20944427
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2010-10-29
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| pubmed:abstractText |
Electrolyzed reduced water (ERW) has attracted much attention because of its therapeutic effects. In the present study, a new culture medium, which we designated Water medium, was developed to elucidate the effects of ERW on the lifespan of Caenorhabditis elegans. Wild-type C. elegans had a significantly shorter lifespan in Water medium than in conventional S medium. However, worms cultured in ERW-Water medium exhibited a significantly extended lifespan (from 11% to 41%) compared with worms cultured in ultrapure water-Water medium. There was no difference between the lifespans of worms cultured in ERW-S medium and ultrapure water-S medium. Nematodes cultured in ultrapure water-Water medium showed significantly higher levels of reactive oxygen species than those cultured in ultrapure water-S medium. Moreover, ERW-Water medium significantly reduced the ROS accumulation induced in the worms by paraquat, suggesting that ERW-Water medium extends the longevity of nematodes at least partly by scavenging ROS.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1347-6947
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
74
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
2011-5
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| pubmed:dateRevised |
2011-8-11
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| pubmed:meshHeading | |
| pubmed:year |
2010
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| pubmed:articleTitle |
Extension of the lifespan of Caenorhabditis elegans by the use of electrolyzed reduced water.
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| pubmed:affiliation |
Graduate School of Systems Life Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan.
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| pubmed:publicationType |
Journal Article
|