20942967

Source:http://linkedlifedata.com/resource/pubmed/id/20942967

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007620, umls-concept:C0018296, umls-concept:C0035820, umls-concept:C0205224, umls-concept:C0334227, umls-concept:C0677886
pubmed:dateCreated	2010-10-27
pubmed:abstractText	We previously identified that Ran protein, a member of the Ras GTPase family, is highly expressed in high grade and high stage serous epithelial ovarian cancers, and that its overexpression is associated with a poor prognosis. Ran is known to contribute to both nucleocytoplasmic transport and cell cycle progression, but its role in ovarian cancer is not well defined.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101147698
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3, http://linkedlifedata.com/resource/pubmed/chemical/ran GTP-Binding Protein
pubmed:status	MEDLINE
pubmed:issn	1476-4598
pubmed:author	pubmed-author:BarrèsVéroniqueV, pubmed-author:LafontaineJulieJ, pubmed-author:Mes-MassonAnne-MarieAM, pubmed-author:OuelletVéroniqueV, pubmed-author:ProvencherDiane MDM, pubmed-author:ToninPatricia NPN
pubmed:issnType	Electronic
pubmed:volume	9
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	272
pubmed:meshHeading	pubmed-meshheading:20942967-Animals, pubmed-meshheading:20942967-Apoptosis, pubmed-meshheading:20942967-Blotting, Western, pubmed-meshheading:20942967-Caspase 3, pubmed-meshheading:20942967-Cell Line, Tumor, pubmed-meshheading:20942967-Cell Proliferation, pubmed-meshheading:20942967-Female, pubmed-meshheading:20942967-Genetic Vectors, pubmed-meshheading:20942967-Humans, pubmed-meshheading:20942967-Immunohistochemistry, pubmed-meshheading:20942967-Lentivirus, pubmed-meshheading:20942967-Membrane Potential, Mitochondrial, pubmed-meshheading:20942967-Mice, pubmed-meshheading:20942967-Mice, SCID, pubmed-meshheading:20942967-Ovarian Neoplasms, pubmed-meshheading:20942967-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:20942967-Xenograft Model Antitumor Assays, pubmed-meshheading:20942967-ran GTP-Binding Protein
pubmed:year	2010
pubmed:articleTitle	An essential role for Ran GTPase in epithelial ovarian cancer cell survival.
pubmed:affiliation	Centre de Recherche du Centre Hospitalier de l'Université de Montréal/Institut du cancer de Montréal,1560 Sherbrooke Est, Montreal H2L 4M1, Canada.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't