Source:http://linkedlifedata.com/resource/pubmed/id/20942442
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2010-11-29
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pubmed:abstractText |
Three new lupane-type triterpenes, lippiolide (1), lippiolidolic acid (2), and lippiolic acid (3), were isolated from aerial parts of Lippia mexicana. Compounds 1 and 2 exhibited a ?-lactone at ring E. The known cycloartane triterpene 5 was also isolated. The structures of these compounds were established on the basis of spectroscopic data and chemical reactions, and the structure of compound 1 was confirmed by X-ray diffraction analysis. Anti-inflammatory activity of compounds 1, 3, and 5 was evaluated in the TPA-induced ear mouse edema model. Lupanes 1 and 3 were more active than cycloartane 5.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1520-6025
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
29
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1969-72
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pubmed:meshHeading |
pubmed-meshheading:20942442-Animals,
pubmed-meshheading:20942442-Anti-Inflammatory Agents,
pubmed-meshheading:20942442-Crystallography, X-Ray,
pubmed-meshheading:20942442-Disease Models, Animal,
pubmed-meshheading:20942442-Edema,
pubmed-meshheading:20942442-Lactones,
pubmed-meshheading:20942442-Lippia,
pubmed-meshheading:20942442-Mice,
pubmed-meshheading:20942442-Molecular Structure,
pubmed-meshheading:20942442-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:20942442-Stereoisomerism,
pubmed-meshheading:20942442-Triterpenes
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pubmed:year |
2010
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pubmed:articleTitle |
Lupane triterpenes with a ?-lactone at ring E, from Lippia mexicana.
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pubmed:affiliation |
Instituto de Qui?mica, Universidad Nacional Auto?noma de Me?xico, Circuito Exterior, Ciudad Universitaria, Coyoaca?n, 04510, DF, Me?xico. emmaldon@servidor.unam.mx
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pubmed:publicationType |
Journal Article
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