Linked Life Data

20942438

Source:http://linkedlifedata.com/resource/pubmed/id/20942438

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
2010-11-10
pubmed:abstractText
Nanocomposites constructed from metallic nanoparticles and amphiphilic copolymers have attracted substantial interest for various potential applications. Here we report on the nanocomposites prepared through cross-linking pluronic micelles with gold nanoparticles. The covalent binding of gold nanoparticles onto the micelles and the thermoresponsibility of the system was followed via ultraviolet-visible spectroscopy, dynamic light scattering, transmission electron microscopy, and fluorescence spectroscopy. The gold-nanoparticle-stabilized pluronic micelles can take thiol-exchange reaction with glutathione and their morphology spontaneously evolved and reassembled into large "vesicular"-like nanocapsules. Obvious temperature responsibility was followed in the gold-nanoparticle-stabilized pluronic micelles system and also the glutathione triggered nanocapsules systems. It is believed that the high stability and glutathione responsibility of the Au-NPs shell-cross-linked micelles allowed for high potential in drug delivery and biosensors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1520-5827
pubmed:author
pubmed:issnType
Electronic
pubmed:day
16
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
16841-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Gold-nanoparticle-stabilized pluronic micelles exhibiting glutathione triggered morphology evolution properties.
pubmed:affiliation
MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't