Linked Life Data

20940368

Source:http://linkedlifedata.com/resource/pubmed/id/20940368

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-4-14
pubmed:abstractText
Cancer is now viewed as a systems biology disease, and oral squamous cell carcinoma (OSCC) can be viewed in a similar fashion. In this paper, we highlight some of the novel molecular events in OSCC, revealed through an integrative strategy of systems biology based on high-throughput omics analysis such as genomics and/or proteomics, the most powerful hypothesis-generating means available today. These approaches have resulted not only in the identification of novel genes for OSCC, but also in more comprehensive networks that describe the mechanisms by which those identified events work, with the promise of developing this knowledge into biomarkers for diagnosis, prognosis, and prediction of therapeutic responses in OSCC patients. Long-term, population-based prospective studies of OSCC patients, and those at high risk of developing OSCC, will then be needed to validate these biomarkers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1544-0591
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
561-72
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Novel molecular events in oral carcinogenesis via integrative approaches.
pubmed:affiliation
State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, No. 14, Sec. 3, Renminnan Road, Chengdu, Sichuan, 610041, China.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't