Linked Life Data

20939590

Source:http://linkedlifedata.com/resource/pubmed/id/20939590

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
21
pubmed:dateCreated
2010-10-29
pubmed:abstractText
The tandem Heck-lactonization reaction between enoates Z-1a,b, E-1a, E-2a-d, Z-2e, 2f, and o-iodophenols (4a-f) was studied in the presence of substoichiometric amounts of Pd(OAc)(2) or PdCl(2), under experimental conditions favoring the cationic mechanism (conditions A, B, and C), leading to coumarins 5a-f and 6a-e. Moderate to excellent yields were obtained under aqueous conditions (conditions A and B). Using electrospray ionization for transferring ions directly from solution to the gas phase, and mass spectrometry for structural assignments, key cationic palladium intermediates have been successfully intercepted and structurally characterized for the first time for this type of reaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1520-6904
pubmed:author
pubmed:issnType
Electronic
pubmed:day
5
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7085-91
pubmed:dateRevised
2011-3-21
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Palladium-catalyzed tandem Heck-lactonization from o-iodophenols and enoates: synthesis of coumarins and the study of the mechanism by electrospray ionization mass spectrometry.
pubmed:affiliation
Laborato?rio de Qui?mica Bioorga?nica (LQB), Nu?cleo de Pesquisas de Produtos Naturais, Centro de Cie?ncias da Sau?de, Bl H, Ilha da Cidade Universita?ria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-590, Brazil.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't