Source:http://linkedlifedata.com/resource/pubmed/id/20939516
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2010-11-29
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pubmed:abstractText |
Three new triterpenoid saponins, platyconic acid B lactone (1), deapio-platyconic acid B lactone (2), and deapio-platycodin D(2) (3), together with 17 known triterpenoid saponins, were isolated from a root extract of Platycodon grandiflorum. The structures of 1-3 were determined on the basis of spectroscopic data interpretation and chemical transformation. Saponins with a platycodigenin or polygalacic acid unit as a sapogenin demonstrated significant inhibitory effects on the proliferation of a small panel of cultured human tumor cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1520-6025
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
29
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1863-7
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pubmed:meshHeading |
pubmed-meshheading:20939516-Antineoplastic Agents,
pubmed-meshheading:20939516-Drug Screening Assays, Antitumor,
pubmed-meshheading:20939516-Humans,
pubmed-meshheading:20939516-Molecular Structure,
pubmed-meshheading:20939516-Plant Roots,
pubmed-meshheading:20939516-Platycodon,
pubmed-meshheading:20939516-Saponins,
pubmed-meshheading:20939516-Triterpenes,
pubmed-meshheading:20939516-Tumor Cells, Cultured
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pubmed:year |
2010
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pubmed:articleTitle |
Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells.
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pubmed:affiliation |
Korea Research Institute of Chemical Technology, Taejeon 305-343, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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