Linked Life Data

20938974

Source:http://linkedlifedata.com/resource/pubmed/id/20938974

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-11-25
pubmed:abstractText
Magnetization transfer contrast has been used commonly for endogenous tissue contrast improvements in angiography, brain, body, and cardiac imaging. Both off-resonant and on-resonant RF pulses can be used to generate magnetization transfer based contrast. In this study, on-resonant magnetization transfer preparation using binomial pulses were optimized and compared with off-resonant magnetization transfer for imaging of coronary veins. Three parameters were studied with simulations and in vivo measurements: flip angle, pulse repetitions, and binomial pulse order. Subsequently, first or second order binomial on-resonant magnetization transfer pulses with eight repetitions of 720° and 240° flip angle were used for coronary vein MRI. Flip angles of 720° yielded contrast enhancement of 115% (P < 0.0006) for first order on-resonant and 95% (P < 0.0006) for off-resonant magnetization transfer. There was no statistically significance difference between off-resonant and on-resonant first order binomial Magnetization transfer at 720°. However, for off-resonance pulses, much more preparation time is needed when compared with the binomials but with considerably reduced specific absorption rate.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1522-2594
pubmed:author
pubmed:copyrightInfo
© 2010 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1849-54
pubmed:dateRevised
2011-9-26
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Optimization of on-resonant magnetization transfer contrast in coronary vein MRI.
pubmed:affiliation
Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural