rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
We have isolated mesenchymal stem cells (MSCs) from tracheal aspirates of premature infants with respiratory distress. Under the influence of transforming growth factor ?, MSCs differentiate into ?-smooth-muscle actin-expressing myofibroblasts. Myofibroblasts are increased in the lungs of patients with bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurely born infants.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
1098-4275
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e1127-33
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pubmed:meshHeading |
pubmed-meshheading:20937656-Birth Weight,
pubmed-meshheading:20937656-Bronchopulmonary Dysplasia,
pubmed-meshheading:20937656-Early Diagnosis,
pubmed-meshheading:20937656-Female,
pubmed-meshheading:20937656-Gestational Age,
pubmed-meshheading:20937656-Humans,
pubmed-meshheading:20937656-Infant, Newborn,
pubmed-meshheading:20937656-Infant, Very Low Birth Weight,
pubmed-meshheading:20937656-Male,
pubmed-meshheading:20937656-Mesenchymal Stem Cells,
pubmed-meshheading:20937656-Prognosis,
pubmed-meshheading:20937656-Reference Values,
pubmed-meshheading:20937656-Respiratory Distress Syndrome, Newborn,
pubmed-meshheading:20937656-Secretory Component,
pubmed-meshheading:20937656-Sex Factors,
pubmed-meshheading:20937656-Stem Cells,
pubmed-meshheading:20937656-Stromal Cells,
pubmed-meshheading:20937656-Suction,
pubmed-meshheading:20937656-Survival Rate,
pubmed-meshheading:20937656-Trachea,
pubmed-meshheading:20937656-Transforming Growth Factor beta1
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pubmed:year |
2010
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pubmed:articleTitle |
Isolation of tracheal aspirate mesenchymal stromal cells predicts bronchopulmonary dysplasia.
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pubmed:affiliation |
Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, MSRBII, 1150 W Medical Center Dr, Ann Arbor, MI 48109-5688, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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