Source:http://linkedlifedata.com/resource/pubmed/id/20936858
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
21
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pubmed:dateCreated |
2010-10-29
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pubmed:abstractText |
Indoles, when treated with dimethyl diazomalonate under catalysis by Cu(acac)(2), undergo C-H insertion reactions regioselectively depending on the substitution pattern on the indole moiety. Indoles where the 3-position is substituted give high yields of the C2-H insertion product. Microwave conditions are also disclosed which show comparable yields with reduced reaction times.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1523-7052
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4956-9
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Direct functionalization of indoles: copper-catalyzed malonyl carbenoid insertions.
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pubmed:affiliation |
Department of Chemistry, The University of Western Ontario, London, Ontario, Canada N6A 5B7.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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