Source:http://linkedlifedata.com/resource/pubmed/id/20936487
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2011-1-3
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pubmed:abstractText |
Intervertebral disc degeneration is now considered to be genetically determined in large part, with environmental factors also playing an important role. The human is known to uniquely exhibit variable numbers of tandem repeat polymorphism within the aggrecan CS1 domain. To date, the analysis of aggrecan's variable numbers of tandem repeat polymorphism has given inconsistent results with respect to the correlation between the allele's size and intervertebral disc degeneration. We wanted to investigate the patterns of the variable numbers of tandem repeat polymorphism in the aggrecan CS1 domain of Koreans, and we analyzed the association between the polymorphism and intervertebral disc degeneration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0942-0940
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
153
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-33
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20936487-Adolescent,
pubmed-meshheading:20936487-Adult,
pubmed-meshheading:20936487-Aged,
pubmed-meshheading:20936487-Aggrecans,
pubmed-meshheading:20936487-Female,
pubmed-meshheading:20936487-Genetic Predisposition to Disease,
pubmed-meshheading:20936487-Humans,
pubmed-meshheading:20936487-Intervertebral Disc,
pubmed-meshheading:20936487-Intervertebral Disc Degeneration,
pubmed-meshheading:20936487-Male,
pubmed-meshheading:20936487-Middle Aged,
pubmed-meshheading:20936487-Polymorphism, Genetic,
pubmed-meshheading:20936487-Tandem Repeat Sequences,
pubmed-meshheading:20936487-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
The association of aggrecan gene polymorphism with the risk of intervertebral disc degeneration.
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pubmed:affiliation |
The Institute of Clinical Research, CHA University, Pochon, Republic of Korea.
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pubmed:publicationType |
Journal Article
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