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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-4-7
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pubmed:abstractText |
Pandemic influenza viruses historically have had few potential sites for N-linked glycosylation on the globular head of the hemagglutinin (HA) on emergence from the avian reservoir. Gain of glycans within antigenic sites of the HA during adaptation to the mammalian lung facilitates immune evasion.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1535-4970
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
183
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
767-73
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pubmed:dateRevised |
2011-8-24
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pubmed:meshHeading |
pubmed-meshheading:20935106-Animals,
pubmed-meshheading:20935106-Antibodies, Neutralizing,
pubmed-meshheading:20935106-Disease Models, Animal,
pubmed-meshheading:20935106-Glycosylation,
pubmed-meshheading:20935106-Hemagglutinin Glycoproteins, Influenza Virus,
pubmed-meshheading:20935106-Influenza A Virus, H1N1 Subtype,
pubmed-meshheading:20935106-Influenza A Virus, H3N2 Subtype,
pubmed-meshheading:20935106-Mice,
pubmed-meshheading:20935106-Mice, Inbred BALB C,
pubmed-meshheading:20935106-Mice, Inbred C57BL,
pubmed-meshheading:20935106-Mutation,
pubmed-meshheading:20935106-Orthomyxoviridae Infections,
pubmed-meshheading:20935106-Pandemics,
pubmed-meshheading:20935106-T-Lymphocytes
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pubmed:year |
2011
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pubmed:articleTitle |
Glycan shielding of the influenza virus hemagglutinin contributes to immunopathology in mice.
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pubmed:affiliation |
Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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