20935017

Source:http://linkedlifedata.com/resource/pubmed/id/20935017

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0332206, umls-concept:C0332281, umls-concept:C0378796, umls-concept:C0436331, umls-concept:C0443252, umls-concept:C1444749, umls-concept:C1522496, umls-concept:C1848822
pubmed:issue	4
pubmed:dateCreated	2011-4-4
pubmed:abstractText	Diabetic nephropathy is characterized by abnormal angiogenesis, and this is driven by several factors, including hyperglycaemia and ischaemia. We investigated the role of vascular endothelial growth factor receptor-2 (VEGFR-2) blockade and its effects on diabetic nephropathy.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8706402
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/8-hydroxy-2'-deoxyguanosine, http://linkedlifedata.com/resource/pubmed/chemical/Deoxyguanosine, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III, http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor..., http://linkedlifedata.com/resource/pubmed/chemical/arginyl-arginyl-lysyl-arginyl-arginy...
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1460-2385
pubmed:author	pubmed-author:ChangYoon SikYS, pubmed-author:ChoiBum SoonBS, pubmed-author:ChungHyun WhaHW, pubmed-author:ChungSungjinS, pubmed-author:KimHyung WookHW, pubmed-author:KimMin YoungMY, pubmed-author:KimYong-SooYS, pubmed-author:LimJi HeeJH, pubmed-author:ParkCheol WheeCW, pubmed-author:ShinSeok JoonSJ
pubmed:issnType	Electronic
pubmed:volume	26
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1173-88
pubmed:meshHeading	pubmed-meshheading:20935017-Albuminuria, pubmed-meshheading:20935017-Animals, pubmed-meshheading:20935017-Apoptosis, pubmed-meshheading:20935017-Blotting, Western, pubmed-meshheading:20935017-Cell Proliferation, pubmed-meshheading:20935017-Deoxyguanosine, pubmed-meshheading:20935017-Diabetes Mellitus, Type 2, pubmed-meshheading:20935017-Diabetic Nephropathies, pubmed-meshheading:20935017-Endothelium, Vascular, pubmed-meshheading:20935017-Immunoenzyme Techniques, pubmed-meshheading:20935017-Male, pubmed-meshheading:20935017-Mice, pubmed-meshheading:20935017-Mice, Inbred C57BL, pubmed-meshheading:20935017-Mice, Mutant Strains, pubmed-meshheading:20935017-Nitric Oxide, pubmed-meshheading:20935017-Nitric Oxide Synthase Type III, pubmed-meshheading:20935017-Obesity, pubmed-meshheading:20935017-Oligopeptides, pubmed-meshheading:20935017-Proto-Oncogene Proteins c-akt, pubmed-meshheading:20935017-RNA, Messenger, pubmed-meshheading:20935017-Renal Insufficiency, pubmed-meshheading:20935017-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:20935017-Signal Transduction, pubmed-meshheading:20935017-Vascular Endothelial Growth Factor A, pubmed-meshheading:20935017-Vascular Endothelial Growth Factor Receptor-2
pubmed:year	2011
pubmed:articleTitle	Long-term blockade of vascular endothelial growth factor receptor-2 aggravates the diabetic renal dysfunction associated with inactivation of the Akt/eNOS-NO axis.
pubmed:affiliation	Division of Nephrology, Department of Internal Medicine, The Catholic University of Korea, Seoul and Division of Nephrology, St. Vincent Hospital, Suwon, Republic of Korea.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't