20933413

Source:http://linkedlifedata.com/resource/pubmed/id/20933413

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0243076, umls-concept:C0456387, umls-concept:C1113688, umls-concept:C1415500
pubmed:issue	22
pubmed:dateCreated	2010-10-19
pubmed:abstractText	A new class of selective orexin 2 antagonist was identified among commercial products. Initial SAR was obtained using commercial derivatives only prior to starting ad hoc medicinal chemistry activities.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Neuropeptide, http://linkedlifedata.com/resource/pubmed/chemical/Triazoles, http://linkedlifedata.com/resource/pubmed/chemical/orexin receptors
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1464-3405
pubmed:author	pubmed-author:AntoliniMarinellaM, pubmed-author:Di FabioRomanoR, pubmed-author:MicheliFabrizioF, pubmed-author:PellacaniAnnalisaA, pubmed-author:PozzanAlfonsoA
pubmed:copyrightInfo	Copyright © 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType	Electronic
pubmed:day	15
pubmed:volume	20
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	6405-7
pubmed:meshHeading	pubmed-meshheading:20933413-Animals, pubmed-meshheading:20933413-Humans, pubmed-meshheading:20933413-Models, Molecular, pubmed-meshheading:20933413-Rats, pubmed-meshheading:20933413-Receptors, G-Protein-Coupled, pubmed-meshheading:20933413-Receptors, Neuropeptide, pubmed-meshheading:20933413-Structure-Activity Relationship, pubmed-meshheading:20933413-Triazoles
pubmed:year	2010
pubmed:articleTitle	2-Methyl-3-furanyl-4H-1,2,4-triazol-3-ylthioamides: a new class of selective orexin 2 antagonists.
pubmed:affiliation	Neurosciences Centre of Excellence, GlaxoSmithKline Medicines Research Centre, Via Fleming 4, 37135 Verona, Italy. fabrizio.micheli@aptuit.com
pubmed:publicationType	Journal Article