rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19-22
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pubmed:dateCreated |
2010-11-5
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pubmed:abstractText |
Proteinase-activated receptor-2 (PAR2) and transient receptor potential vanilloid-1 (TRPV1) are co-localized in the primary afferents, and the trans-activation of TRPV1 by PAR2 activation is involved in processing of somatic pain. Given evidence for contribution of PAR2 to pancreatic pain, the present study aimed at clarifying the involvement of TRPV1 in processing of pancreatic pain by the proteinase/PAR2 pathway in mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Caerulein,
http://linkedlifedata.com/resource/pubmed/chemical/Capsaicin,
http://linkedlifedata.com/resource/pubmed/chemical/Guanidines,
http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-fos,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, PAR-2,
http://linkedlifedata.com/resource/pubmed/chemical/TRPV Cation Channels,
http://linkedlifedata.com/resource/pubmed/chemical/TRPV1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/capsazepine,
http://linkedlifedata.com/resource/pubmed/chemical/nafamostat,
http://linkedlifedata.com/resource/pubmed/chemical/seryl-leucyl-isoleucyl-glycyl--argin...
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
643-50
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pubmed:meshHeading |
pubmed-meshheading:20932849-Acute Disease,
pubmed-meshheading:20932849-Animals,
pubmed-meshheading:20932849-Caerulein,
pubmed-meshheading:20932849-Capsaicin,
pubmed-meshheading:20932849-Disease Models, Animal,
pubmed-meshheading:20932849-Gene Expression Regulation,
pubmed-meshheading:20932849-Guanidines,
pubmed-meshheading:20932849-Hyperalgesia,
pubmed-meshheading:20932849-Male,
pubmed-meshheading:20932849-Mice,
pubmed-meshheading:20932849-Oligopeptides,
pubmed-meshheading:20932849-Pain,
pubmed-meshheading:20932849-Pancreatitis,
pubmed-meshheading:20932849-Proto-Oncogene Proteins c-fos,
pubmed-meshheading:20932849-Receptor, PAR-2,
pubmed-meshheading:20932849-Spinal Cord,
pubmed-meshheading:20932849-TRPV Cation Channels
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pubmed:year |
2010
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pubmed:articleTitle |
The proteinase/proteinase-activated receptor-2/transient receptor potential vanilloid-1 cascade impacts pancreatic pain in mice.
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pubmed:affiliation |
Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, Higashi-Osaka, Japan.
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pubmed:publicationType |
Journal Article
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