Source:http://linkedlifedata.com/resource/pubmed/id/20930549
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2011-1-13
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pubmed:abstractText |
Due to the small volume and high density of breast tissue in Asian women, particularly younger women, mammographic diagnosis is sometimes non-conclusive, with a Breast Imaging Reporting and Data System (BI-RADS) result of 0. No alternative based on blood biomarkers has yet succeeded in discriminating between patients with breast cancer (BC) and those with benign breast disease (BBD) among BI-RADS 0 patients. In our study, 84 BC and 94 BBD patients with mammographic results and confirmed pathologic information were enrolled and categorized into two groups, namely, 79 BC and 73 BBD patients with BI-RADS 1-5 and 5 BC and 21 BBD patients with BI-RADS 0. RNA extracted from peripheral blood samples collected in PAXgene (TM) tubes was analyzed after NuGEN WT-Ovation (TM) RNA amplification using Affymetrix GeneChip.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1555-8576
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1235-9
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pubmed:meshHeading |
pubmed-meshheading:20930549-Adult,
pubmed-meshheading:20930549-Aged,
pubmed-meshheading:20930549-Asian Continental Ancestry Group,
pubmed-meshheading:20930549-Biological Markers,
pubmed-meshheading:20930549-Breast Diseases,
pubmed-meshheading:20930549-Breast Neoplasms,
pubmed-meshheading:20930549-Female,
pubmed-meshheading:20930549-Humans,
pubmed-meshheading:20930549-Mammography,
pubmed-meshheading:20930549-Microarray Analysis,
pubmed-meshheading:20930549-Middle Aged,
pubmed-meshheading:20930549-Nucleic Acid Amplification Techniques,
pubmed-meshheading:20930549-RNA, Messenger
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pubmed:year |
2011
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pubmed:articleTitle |
Using peripheral blood mRNA signature to distinguish between breast cancer and benign breast disease in non-conclusive mammography patients.
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pubmed:affiliation |
Fudan University Shanghai Cancer Center, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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