20930159

Source:http://linkedlifedata.com/resource/pubmed/id/20930159

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0009195, umls-concept:C0037083, umls-concept:C0074992, umls-concept:C0232338, umls-concept:C0333516, umls-concept:C0392756, umls-concept:C1710082, umls-concept:C2349975
pubmed:issue	11
pubmed:dateCreated	2010-10-26
pubmed:abstractText	We sought to demonstrate that tumor necrosis factor (TNF)-?, via sphingosine-1-phosphate signaling, has the potential to alter cochlear blood flow and thus, cause ischemic hearing loss.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/MOP-84402, http://linkedlifedata.com/resource/pubmed/grant/P20-RR017686, http://linkedlifedata.com/resource/pubmed/grant/R01-DC04280
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0235266
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Calcium, http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G, http://linkedlifedata.com/resource/pubmed/chemical/Lysophospholipids, http://linkedlifedata.com/resource/pubmed/chemical/Phosphotransferases (Alcohol Group..., http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor, http://linkedlifedata.com/resource/pubmed/chemical/Sphingosine, http://linkedlifedata.com/resource/pubmed/chemical/TNFR-Fc fusion protein, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha, http://linkedlifedata.com/resource/pubmed/chemical/sphingosine 1-phosphate, http://linkedlifedata.com/resource/pubmed/chemical/sphingosine kinase
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1524-4628
pubmed:author	pubmed-author:BackxPeter HPH, pubmed-author:BolzSteffen-SebastianSS, pubmed-author:CanisMartinM, pubmed-author:DiehlChristian DCD, pubmed-author:IvanovKarolinaK, pubmed-author:LidingtonDarcyD, pubmed-author:ReimannKatrinK, pubmed-author:SchererElias QEQ, pubmed-author:StriethSebastianS, pubmed-author:Voigtlaender-BolzJuliaJ, pubmed-author:WangemannPhilineP, pubmed-author:WierW GilWG, pubmed-author:YangJingliJ
pubmed:issnType	Electronic
pubmed:volume	41
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2618-24
pubmed:meshHeading	pubmed-meshheading:20930159-Adult, pubmed-meshheading:20930159-Animals, pubmed-meshheading:20930159-Calcium, pubmed-meshheading:20930159-Cochlea, pubmed-meshheading:20930159-Gerbillinae, pubmed-meshheading:20930159-Guinea Pigs, pubmed-meshheading:20930159-Hearing Loss, pubmed-meshheading:20930159-Humans, pubmed-meshheading:20930159-Immunoglobulin G, pubmed-meshheading:20930159-Lysophospholipids, pubmed-meshheading:20930159-Microvessels, pubmed-meshheading:20930159-Models, Animal, pubmed-meshheading:20930159-Phosphotransferases (Alcohol Group Acceptor), pubmed-meshheading:20930159-Receptors, Tumor Necrosis Factor, pubmed-meshheading:20930159-Regional Blood Flow, pubmed-meshheading:20930159-Signal Transduction, pubmed-meshheading:20930159-Sphingosine, pubmed-meshheading:20930159-Spiral Ligament of Cochlea, pubmed-meshheading:20930159-Treatment Outcome, pubmed-meshheading:20930159-Tumor Necrosis Factor-alpha, pubmed-meshheading:20930159-Vasoconstriction
pubmed:year	2010
pubmed:articleTitle	Tumor necrosis factor-? enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine-1-phosphate signaling.
pubmed:affiliation	Hals-Nasen-Ohrenklinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural