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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-10-21
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pubmed:abstractText |
Multiple sclerosis (MS) is the endpoint of a complex and still poorly understood process which results in inflammation, demyelination and axonal and neuronal degeneration. Since the first description of MS, psychological stress has been suggested to be one of the trigger factors in the onset and/or relapse of symptoms. However, data from animal models of MS, such as experimental autoimmune encephalomyelitis (EAE) are inconsistent and the effect of stress on EAE onset and severity depends on duration and time of application of the stress protocol and the underlying mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1742-2094
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
60
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20929574-Analysis of Variance,
pubmed-meshheading:20929574-Animals,
pubmed-meshheading:20929574-Blotting, Western,
pubmed-meshheading:20929574-Corticosterone,
pubmed-meshheading:20929574-Dinoprostone,
pubmed-meshheading:20929574-Encephalomyelitis, Autoimmune, Experimental,
pubmed-meshheading:20929574-Lipid Peroxidation,
pubmed-meshheading:20929574-Male,
pubmed-meshheading:20929574-Myelin Proteins,
pubmed-meshheading:20929574-Myelin-Associated Glycoprotein,
pubmed-meshheading:20929574-Peroxidase,
pubmed-meshheading:20929574-Prostaglandin D2,
pubmed-meshheading:20929574-Radioimmunoassay,
pubmed-meshheading:20929574-Rats,
pubmed-meshheading:20929574-Restraint, Physical,
pubmed-meshheading:20929574-Spinal Cord,
pubmed-meshheading:20929574-Stress, Physiological
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pubmed:year |
2010
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pubmed:articleTitle |
Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated.
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pubmed:affiliation |
Department of Pharmacology, Faculty Medicine, University Complutense, Centro de Investigación Biomédica en red de Salud Mental (CIBERSA), Granada, Spain. bgomezpe@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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