Source:http://linkedlifedata.com/resource/pubmed/id/20926194
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
2010-11-24
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pubmed:abstractText |
An outbreak of trypanosomoasis caused by Trypanosoma evansi involving horses, camels and donkeys occurred in a farm in Israel. A longitudinal study of two outbreak phases was conducted which included clinical monitoring, blood smears, packed cell volume (PCV), serology and polymerase chain reaction (PCR) followed by reverse dot blot (RDB) for the molecular detection of infection. This was the first reported T. evansi outbreak in domestic animals in Israel. Most of the camels on the farm (8/10; 80%) were diagnosed with T. evansi infection whereas infection was less prevalent in the horses (3/7; 43%) and donkeys (6/13; 46%). Clinical disease was evident in 4 camels and 1 horse exhibiting characteristic clinical signs, anemia and parasitemia detected on blood smears and by positive RDB. Six other animals were diagnosed as asymptomatic latent carriers by positive RDB and 6 additional animals were only seropositive and were considered suspected carriers. A significant difference was found in the mean PCV between symptomatic and latent carriers with severe anemia observed only in the symptomatic animals. An anaphylactic-like reaction, fatal in one case, was observed in 2 camels diagnosed with severe trypanosome parasitemia immediately following treatment with melarsenoxide cysteamine. Furthermore, recurrence of infection was documented in one camel 4 months post treatment.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1873-2550
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
174
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
317-22
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pubmed:meshHeading |
pubmed-meshheading:20926194-Animals,
pubmed-meshheading:20926194-Arsenicals,
pubmed-meshheading:20926194-Camels,
pubmed-meshheading:20926194-Disease Outbreaks,
pubmed-meshheading:20926194-Equidae,
pubmed-meshheading:20926194-Female,
pubmed-meshheading:20926194-Israel,
pubmed-meshheading:20926194-Longitudinal Studies,
pubmed-meshheading:20926194-Male,
pubmed-meshheading:20926194-Species Specificity,
pubmed-meshheading:20926194-Trypanocidal Agents,
pubmed-meshheading:20926194-Trypanosomiasis
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pubmed:year |
2010
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pubmed:articleTitle |
Longitudinal study of an outbreak of Trypanosoma evansi infection in equids and dromedary camels in Israel.
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pubmed:affiliation |
Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, P.O. Box 12, Rehovot 76100, Israel. berlin@agri.huji.ac.il
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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