Linked Life Data

20924131

Source:http://linkedlifedata.com/resource/pubmed/id/20924131

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
2010-11-16
pubmed:abstractText
Phosphorylated histone H2AX (?H2AX) serves as a biomarker for formation of DNA double-strand break repair complexes. A quantitative pharmacodynamic immunofluorescence assay for ?H2AX was developed, validated, and tested in human tumor xenograft models with the use of clinically relevant procedures.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1078-0432
pubmed:author
pubmed:copyrightInfo
©2010 AACR.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5447-57
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Development of a validated immunofluorescence assay for ?H2AX as a pharmacodynamic marker of topoisomerase I inhibitor activity.
pubmed:affiliation
Laboratory of Human Toxicology and Pharmacology, Applied/Developmental Research Support Directorate, Science Applications International Corporation-Frederick, Inc., NationalCancer Institute-Frederick, Frederick, MD 21702, USA. kindersr@mail.nih.gov
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural, Validation Studies