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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-11-11
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pubmed:abstractText |
Multiple carcinogenesis is one of the major characteristics of human hepatocellular carcinoma (HCC). The history of multiple tumors, that is, whether they derive from a common precancerous or cancerous ancestor or individually from hepatocytes, is a major clinical issue. Multiple HCC is clinically classified as either intratumor metastasis (IM) or multicentric carcinogenesis (MC). Molecular markers that differentiate IM and MC are of interest to clinical practitioners because the clinical diagnoses of IM and MC often lead to different therapies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
530
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pubmed:meshHeading |
pubmed-meshheading:20923573-Carcinoma, Hepatocellular,
pubmed-meshheading:20923573-Chromosome Aberrations,
pubmed-meshheading:20923573-Comparative Genomic Hybridization,
pubmed-meshheading:20923573-DNA Methylation,
pubmed-meshheading:20923573-Epigenesis, Genetic,
pubmed-meshheading:20923573-Epigenomics,
pubmed-meshheading:20923573-Genes, Tumor Suppressor,
pubmed-meshheading:20923573-Humans,
pubmed-meshheading:20923573-Liver Neoplasms,
pubmed-meshheading:20923573-Models, Genetic,
pubmed-meshheading:20923573-Mutation,
pubmed-meshheading:20923573-Neoplasm Metastasis,
pubmed-meshheading:20923573-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20923573-Promoter Regions, Genetic
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.
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pubmed:affiliation |
Research Institute, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1-3-3 Nakamichi, Higashinari-ku, Osaka, 537-8511, Japan.
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pubmed:publicationType |
Journal Article
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