Source:http://linkedlifedata.com/resource/pubmed/id/20923548
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2010-10-19
|
pubmed:abstractText |
The capacity of Plasmodium falciparum-infected erythrocytes to bind uninfected erythrocytes (rosetting) is associated with severe malaria in African children. Rosetting is mediated by a subset of the variant surface antigens PfEMP1 targeted by protective antibody responses. Analysis of the response to rosette-forming parasites and their PfEMP1 adhesive domains is essential for understanding the acquisition of protection against severe malaria. To this end, the antibody response to a rosetting variant was analysed in children recruited with severe or uncomplicated malaria or asymptomatic P. falciparum infection.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1475-2875
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
267
|
pubmed:meshHeading |
pubmed-meshheading:20923548-Adult,
pubmed-meshheading:20923548-Antibodies, Protozoan,
pubmed-meshheading:20923548-Benin,
pubmed-meshheading:20923548-Carrier State,
pubmed-meshheading:20923548-Child,
pubmed-meshheading:20923548-Child, Preschool,
pubmed-meshheading:20923548-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20923548-Female,
pubmed-meshheading:20923548-Humans,
pubmed-meshheading:20923548-Immunoglobulin G,
pubmed-meshheading:20923548-Malaria, Falciparum,
pubmed-meshheading:20923548-Male,
pubmed-meshheading:20923548-Parasitology,
pubmed-meshheading:20923548-Plasmodium falciparum,
pubmed-meshheading:20923548-Protozoan Proteins
|
pubmed:year |
2010
|
pubmed:articleTitle |
The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese children.
|
pubmed:affiliation |
Institut Pasteur, Unité d'Immunologie Moléculaire des Parasites, F-75015 Paris, France.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|