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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-11-12
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pubmed:abstractText |
Mesenchymal stromal cells (MSCs) are pluripotent cells that have immunosuppressive effects both in vitro and in experimental colitis. Promising results of MSC therapy have been obtained in patients with severe graft versus host disease of the gut. Our objective was to determine the safety and feasibility of autologous bone marrow derived MSC therapy in patients with refractory Crohn's disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1468-3288
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pubmed:author |
pubmed-author:DuijvesteinMarjolijnM,
pubmed-author:FibbeWillem EWE,
pubmed-author:FidderHerma HHH,
pubmed-author:HommesDaniel WDW,
pubmed-author:KoningFritsF,
pubmed-author:Kooy-WinkelaarEngelina M CEM,
pubmed-author:RoelofsHeleneH,
pubmed-author:VerhaarAuke PAP,
pubmed-author:VerspagetHenricus WHW,
pubmed-author:VosAnne Christine WAC,
pubmed-author:WendrichBarbara BBB,
pubmed-author:WildenbergManon EME,
pubmed-author:ZwagingaJaap JanJJ,
pubmed-author:van den BrinkGijs RGR
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pubmed:issnType |
Electronic
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1662-9
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pubmed:meshHeading |
pubmed-meshheading:20921206-Adult,
pubmed-meshheading:20921206-Cell Differentiation,
pubmed-meshheading:20921206-Cell Proliferation,
pubmed-meshheading:20921206-Cells, Cultured,
pubmed-meshheading:20921206-Colonoscopy,
pubmed-meshheading:20921206-Crohn Disease,
pubmed-meshheading:20921206-Cytokines,
pubmed-meshheading:20921206-Dose-Response Relationship, Immunologic,
pubmed-meshheading:20921206-Epidemiologic Methods,
pubmed-meshheading:20921206-Female,
pubmed-meshheading:20921206-Humans,
pubmed-meshheading:20921206-Immune Tolerance,
pubmed-meshheading:20921206-Immunity, Mucosal,
pubmed-meshheading:20921206-Male,
pubmed-meshheading:20921206-Mesenchymal Stem Cell Transplantation,
pubmed-meshheading:20921206-Stromal Cells,
pubmed-meshheading:20921206-T-Lymphocyte Subsets,
pubmed-meshheading:20921206-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study.
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. m.duijvestein@lumc.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
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