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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-10-5
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pubmed:abstractText |
Infiltrating ductal carcinoma (IDC) is the most common malignant breast cancer in women, and genetic factors appear to play a significant role in the susceptibility to IDC. Alteration of DNA methylation is an epigenetic change in human cancers, including breast cancer. DNA-methyltransferase 1 (DNMT1) is a major enzyme that determines genomic methylation patterns. In order to clarify the association of DNMT1 polymorphisms with IDC, a case-control study was conducted in women from the Heilongjiang Province, in the northeast of China.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1938-0666
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-7
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pubmed:meshHeading |
pubmed-meshheading:20920981-Adult,
pubmed-meshheading:20920981-Aged,
pubmed-meshheading:20920981-Alleles,
pubmed-meshheading:20920981-Breast Neoplasms,
pubmed-meshheading:20920981-Carcinoma, Ductal, Breast,
pubmed-meshheading:20920981-Case-Control Studies,
pubmed-meshheading:20920981-Chi-Square Distribution,
pubmed-meshheading:20920981-China,
pubmed-meshheading:20920981-Exons,
pubmed-meshheading:20920981-Female,
pubmed-meshheading:20920981-Haplotypes,
pubmed-meshheading:20920981-Humans,
pubmed-meshheading:20920981-Middle Aged,
pubmed-meshheading:20920981-Odds Ratio,
pubmed-meshheading:20920981-Polymorphism, Single Nucleotide,
pubmed-meshheading:20920981-Receptors, Estrogen,
pubmed-meshheading:20920981-Receptors, Progesterone,
pubmed-meshheading:20920981-Repressor Proteins,
pubmed-meshheading:20920981-Tumor Suppressor Protein p53,
pubmed-meshheading:20920981-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Association of DNMT1 gene polymorphisms in exons with sporadic infiltrating ductal breast carcinoma among Chinese Han women in the Heilongjiang Province.
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pubmed:affiliation |
Department of Immunology, Harbin Medical University, China Institute of Cancer Prevention and Treatment, Harbin Medical University, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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