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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-10-21
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pubmed:abstractText |
Esophageal squamous cell carcinomas (ESCC) are usually asymptomatic and go undetected until they are incurable. Cytological screening is one strategy to detect ESCC at an early stage and has shown promise in previous studies, although improvement in sensitivity and specificity are needed. Proteases modulate cancer progression by facilitating tumor invasion and metastasis. In the current study, matrix metalloproteinases (MMPs) were studied in a search for new early detection markers for ESCC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1479-5876
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pubmed:author |
pubmed-author:ChuaquiRodrigo FRF,
pubmed-author:DawseySanford MSM,
pubmed-author:Emmert-BuckMichael RMR,
pubmed-author:EricksonHeidi SHS,
pubmed-author:GoldsteinAlisa MAM,
pubmed-author:JiP YPY,
pubmed-author:MukherjeeSumanaS,
pubmed-author:RichardsonAnnely MAM,
pubmed-author:Rodriguez-CanalesJaimeJ,
pubmed-author:RothMark JMJ,
pubmed-author:TangreaMichael AMA,
pubmed-author:TaylorPhilip RPR,
pubmed-author:YanWushengW
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91
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pubmed:meshHeading |
pubmed-meshheading:20920372-Adult,
pubmed-meshheading:20920372-Aged,
pubmed-meshheading:20920372-Carcinoma, Squamous Cell,
pubmed-meshheading:20920372-Enzyme Activation,
pubmed-meshheading:20920372-Esophageal Neoplasms,
pubmed-meshheading:20920372-Female,
pubmed-meshheading:20920372-Humans,
pubmed-meshheading:20920372-Male,
pubmed-meshheading:20920372-Matrix Metalloproteinases,
pubmed-meshheading:20920372-Middle Aged,
pubmed-meshheading:20920372-Polymerase Chain Reaction
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pubmed:year |
2010
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pubmed:articleTitle |
Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma.
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pubmed:affiliation |
Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
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