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rdf:type |
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lifeskim:mentions |
umls-concept:C0007257,
umls-concept:C0007600,
umls-concept:C0017262,
umls-concept:C0017638,
umls-concept:C0036667,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0205250,
umls-concept:C0312418,
umls-concept:C0442805,
umls-concept:C2911684
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pubmed:dateCreated |
2010-10-15
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pubmed:abstractText |
Studies have shown that Dickkopf-1 (DKK-1) is involved in tumorigenesis. Recently, we found that 9 out of 12 human glioma cell lines had high level of DKK-1 protein while the other 3 had very low or non-detectable level of DKK-1. The aim of this study is to further examine the function of DKK-1 in glioma cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, Alkylating,
http://linkedlifedata.com/resource/pubmed/chemical/BAX protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CASP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carmustine,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/DKK1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/bcl-2-Associated X Protein
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pubmed:status |
MEDLINE
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pubmed:issn |
1756-9966
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131
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pubmed:meshHeading |
pubmed-meshheading:20920327-Antineoplastic Agents, Alkylating,
pubmed-meshheading:20920327-Apoptosis,
pubmed-meshheading:20920327-Blotting, Western,
pubmed-meshheading:20920327-Brain Neoplasms,
pubmed-meshheading:20920327-Carmustine,
pubmed-meshheading:20920327-Caspase 3,
pubmed-meshheading:20920327-Cell Line, Tumor,
pubmed-meshheading:20920327-Cell Shape,
pubmed-meshheading:20920327-Flow Cytometry,
pubmed-meshheading:20920327-Glioma,
pubmed-meshheading:20920327-Humans,
pubmed-meshheading:20920327-Immunohistochemistry,
pubmed-meshheading:20920327-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:20920327-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:20920327-RNA, Messenger,
pubmed-meshheading:20920327-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20920327-Transfection,
pubmed-meshheading:20920327-Up-Regulation,
pubmed-meshheading:20920327-bcl-2-Associated X Protein
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pubmed:year |
2010
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pubmed:articleTitle |
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
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pubmed:affiliation |
Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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