Linked Life Data

2090286

Source:http://linkedlifedata.com/resource/pubmed/id/2090286

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-6-3
pubmed:abstractText
We reviewed published studies on the association of age at natural menopause and cigarette smoking. All demonstrated an earlier median or mean age of menopause among smokers; for current smokers vs noncurrent smokers the difference ranged from 0.8 to 1.7 years. For studies that presented suitable data, we computed prevalence odds ratios of menopause for current smokers vs never-smokers, current smokers vs noncurrent smokers, and former smokers vs never-smokers. The Mantel-Haenzel summary odds ratios and 95% confidence intervals for these contrasts were: 1.9 (1.7-2.2), 1.7 (1.5-1.9), and 1.3 (1.0-1.7). Studies that presented data on amount of cigarettes smoked per day demonstrated "dose-response" trends when analyzed using the Mantel-Haenszel extension. The consistency of results across studies, the persistence of the effect when age and other covariates were considered, and the dose-response relation all support the hypothesis that smoking increases the risk of early menopause.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1044-3983
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
474-80
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Cigarette smoking and the risk of natural menopause.
pubmed:affiliation
Veterans Affairs Medical Center, White River Junction, Vermont.
pubmed:publicationType
Journal Article, Review