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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1991-5-30
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pubmed:abstractText |
Central to immunization programmes is that hepatitis B virus infection in infancy is much more likely to result in the chronic carrier state than if infection occurs in adulthood. In areas of high endemicity like south-eastern Asia most infections occur when chronically infected women transmit hepatitis B virus to their newborns or when chronically infected children transmit the virus to other children. In the Netherlands, the endemicity is considered low; seroprevalence studies showed that 0.8% of the pregnant women are HBsAg-positive. To prevent mother to child transmission of hepatitis B a national immunization program has recently been implemented to prevent perinatal infection in approximately 450 neonates each year. Horizontal transmission of hepatitis B virus also seems possible in children since persistent carriers are found in (medical) centres and institutions for mentally handicapped. Since hepatitis B infections acquired during early childhood are likely to progress to chronicity and liver disease in adult life some risk factors for children in the Netherlands to contract hepatitis B infection are described and the immunization strategy is discussed.
|
pubmed:language |
dut
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0376-7442
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
203-11
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pubmed:dateRevised |
2008-3-24
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pubmed:meshHeading |
pubmed-meshheading:2089733-Child,
pubmed-meshheading:2089733-Child, Preschool,
pubmed-meshheading:2089733-Female,
pubmed-meshheading:2089733-Hepatitis B,
pubmed-meshheading:2089733-Hepatitis B Antigens,
pubmed-meshheading:2089733-Humans,
pubmed-meshheading:2089733-Infant,
pubmed-meshheading:2089733-Infant, Newborn,
pubmed-meshheading:2089733-Maternal-Fetal Exchange,
pubmed-meshheading:2089733-Netherlands,
pubmed-meshheading:2089733-Pregnancy
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pubmed:year |
1990
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pubmed:articleTitle |
[Hepatitis B in children].
|
pubmed:affiliation |
Afd. Inwendige Geneeskunde II, Academisch Ziekenhuis Dijkzigt, Rotterdam.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
|