Source:http://linkedlifedata.com/resource/pubmed/id/20887828
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
48
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pubmed:dateCreated |
2010-11-15
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pubmed:abstractText |
Influenza vaccination is now recommended for all ages; CDC pneumococcal polysaccharide vaccination (PPV) recommendations are comorbidity-based in nonelderly patients. We constructed a Markov model to estimate the cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds. Patients were followed for 10 years, with differing time horizons examined in sensitivity analyses. With 100% vaccine uptake, dual vaccination cost $37,700/QALY gained compared to a CDC recommendation strategy; with observed vaccine uptake, dual vaccination cost $5,300/QALY. Results were sensitive to shorter time horizons, favoring CDC recommendations. We found dual vaccination of all 50-year-olds economically reasonable. Shorter duration models may not fully account for PPV effectiveness.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1873-2518
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7620-5
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pubmed:dateRevised |
2011-11-10
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pubmed:meshHeading |
pubmed-meshheading:20887828-Centers for Disease Control and Prevention (U.S.),
pubmed-meshheading:20887828-Cost-Benefit Analysis,
pubmed-meshheading:20887828-Humans,
pubmed-meshheading:20887828-Influenza, Human,
pubmed-meshheading:20887828-Influenza Vaccines,
pubmed-meshheading:20887828-Markov Chains,
pubmed-meshheading:20887828-Middle Aged,
pubmed-meshheading:20887828-Pneumococcal Infections,
pubmed-meshheading:20887828-Pneumococcal Vaccines,
pubmed-meshheading:20887828-Quality-Adjusted Life Years,
pubmed-meshheading:20887828-United States,
pubmed-meshheading:20887828-Vaccination
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pubmed:year |
2010
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pubmed:articleTitle |
Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds.
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pubmed:affiliation |
University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. kjs8@pitt.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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