Source:http://linkedlifedata.com/resource/pubmed/id/20887794
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2010-12-3
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pubmed:abstractText |
Developmental dysplasia of the hip (DDH), formerly known as congenital dislocation of the hip, comprises a spectrum of abnormalities, including abnormal acetabular shape (dysplasia) and malposition of the femoral head during embryonic, fetal and infantile growth periods. Genetic factors play a considerable role in the pathogenesis of DDH. As a key regulator for the hindlimb outgrowth and identification, Tbx4 may be involved in the aetiology and pathogenesis of DDH. Our objective is to evaluate whether the Tbx4 (rs3744438 and rs3744448) single nucleotide polymorphisms (SNPs) are associated with DDH in Chinese.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1522-9653
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010. Published by Elsevier Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1592-5
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pubmed:meshHeading |
pubmed-meshheading:20887794-Case-Control Studies,
pubmed-meshheading:20887794-Child,
pubmed-meshheading:20887794-Child, Preschool,
pubmed-meshheading:20887794-Female,
pubmed-meshheading:20887794-Genetic Predisposition to Disease,
pubmed-meshheading:20887794-Genotype,
pubmed-meshheading:20887794-Hip Dislocation, Congenital,
pubmed-meshheading:20887794-Humans,
pubmed-meshheading:20887794-Infant,
pubmed-meshheading:20887794-Joint Instability,
pubmed-meshheading:20887794-Male,
pubmed-meshheading:20887794-Polymorphism, Single Nucleotide,
pubmed-meshheading:20887794-Sex Factors,
pubmed-meshheading:20887794-T-Box Domain Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Association of a single nucleotide polymorphism in Tbx4 with developmental dysplasia of the hip: a case-control study.
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pubmed:affiliation |
The Center of Diagnosis and Treatment for Joint Disease, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing 210008, Jiangsu, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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