Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-12-14
pubmed:abstractText
Central neurocytomas (CN) are rare tumors. Since their first description in 1982, the number of case reports and series has been rapidly increasing. Although they are considered low-grade neoplasms, they can be associated with an aggressive primary course or recurrence after resection. The cellular origin of central neurocytoma (CN) and the molecular events leading to tumorigenesis have been largely unknown. Here, we present a review of the scientific literature contributing to our knowledge of CN focusing on cellular origin and oncogenic alterations, and how these findings inform areas amenable to future research and therapeutic intervention. Our discussion is expanded to include important and related insights into the cellular origin and classification of central nervous system tumors.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1532-2653
pubmed:author
pubmed:copyrightInfo
2010. Published by Elsevier Ltd.
pubmed:issnType
Electronic
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
The molecular pathology of central neurocytomas.
pubmed:affiliation
Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, California 94143, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural