rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-9-30
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pubmed:abstractText |
Pancreatic islet transplantation (PIT) represents a potential curative treatment for patients with type 1 diabetes, but only 10-15% of patients remain insulin independent 5 years post-transplant. It is not known whether intrinsic insulin resistance exacerbated by immunosuppression plays a pivotal role in low graft survival. The study objective was to understand the changes in insulin resistance, glucose effectiveness (S(g)) and free fatty acid dynamics (FFAd) before and after PIT.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1463-1326
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 Blackwell Publishing Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
994-1003
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20880346-Adolescent,
pubmed-meshheading:20880346-Adult,
pubmed-meshheading:20880346-Aged,
pubmed-meshheading:20880346-Diabetes Mellitus, Type 1,
pubmed-meshheading:20880346-Fatty Acids, Nonesterified,
pubmed-meshheading:20880346-Female,
pubmed-meshheading:20880346-Glucose,
pubmed-meshheading:20880346-Glucose Tolerance Test,
pubmed-meshheading:20880346-Humans,
pubmed-meshheading:20880346-Insulin,
pubmed-meshheading:20880346-Insulin Resistance,
pubmed-meshheading:20880346-Islets of Langerhans Transplantation,
pubmed-meshheading:20880346-Male,
pubmed-meshheading:20880346-Middle Aged,
pubmed-meshheading:20880346-Treatment Outcome,
pubmed-meshheading:20880346-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Correction of insulin sensitivity and glucose disposal after pancreatic islet transplantation: preliminary results.
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pubmed:affiliation |
Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI 53792-7375, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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