Linked Life Data

20879879

Source:http://linkedlifedata.com/resource/pubmed/id/20879879

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2010-9-30
pubmed:databankReference
pubmed:abstractText
Spleen tyrosine kinase (Syk) is an important modulator of immune signaling. The objective of this phase 2 study was to evaluate the efficacy and safety of R788, an oral inhibitor of Syk, in patients with active rheumatoid arthritis despite methotrexate therapy.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1533-4406
pubmed:author
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
363
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1303-12
pubmed:dateRevised
2011-11-2
pubmed:meshHeading
pubmed-meshheading:20879879-Adult, pubmed-meshheading:20879879-Aged, pubmed-meshheading:20879879-Aged, 80 and over, pubmed-meshheading:20879879-Antirheumatic Agents, pubmed-meshheading:20879879-Arthritis, Rheumatoid, pubmed-meshheading:20879879-Double-Blind Method, pubmed-meshheading:20879879-Drug Therapy, Combination, pubmed-meshheading:20879879-Female, pubmed-meshheading:20879879-Humans, pubmed-meshheading:20879879-Intracellular Signaling Peptides and Proteins, pubmed-meshheading:20879879-Male, pubmed-meshheading:20879879-Methotrexate, pubmed-meshheading:20879879-Middle Aged, pubmed-meshheading:20879879-Oxazines, pubmed-meshheading:20879879-Protein Kinase Inhibitors, pubmed-meshheading:20879879-Protein-Tyrosine Kinases, pubmed-meshheading:20879879-Pyridines, pubmed-meshheading:20879879-Statistics, Nonparametric, pubmed-meshheading:20879879-Treatment Outcome
pubmed:year
2010
pubmed:articleTitle
An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis.
pubmed:affiliation
Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. mweinblatt@partners.org
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study, Clinical Trial, Phase II