Linked Life Data

20878640

Source:http://linkedlifedata.com/resource/pubmed/id/20878640

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-10-14
pubmed:abstractText
Long-range studies on the chemistry of two strained ring systems, cyclopropanes and fullerenes, converged on a challenge in biology, in vivo gene delivery. The new protocol of gene delivery employing a tailor-designed amino fullerene represents the third protocol after the two using virus and lipid delivery agents, none of which are universally useful. The amino fullerene delivers an EGFP and an insulin-2 gene to mice with efficiency superior to and selectivity distinct from those achieved by the conventional lipid-based delivery agents. The studies demonstrate the power of organic synthesis as driven by scientifically and socially important subjects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1528-0691
pubmed:author
pubmed:copyrightInfo
© 2010 The Japan Chemical Journal Forum and Wiley Periodicals, Inc.
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
260-70
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
In vitro and in vivo gene delivery with tailor-designed aminofullerenes.
pubmed:affiliation
Department of Chemistry, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. nakamura@chem.s.u-tokyo.ac.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't