Linked Life Data

20877784

Source:http://linkedlifedata.com/resource/pubmed/id/20877784

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
2010-11-10
pubmed:abstractText
A new series of 4-aryl-2,6-dimethyl-1,4-dihydropyridines, characterized by ester or ketone functions at positions 3 and 5, has been synthesized. Structural and conformational properties, concerning the dihydropyridine ring and the orientation (synplanar/antiperiplanar) of the substituents have been investigated in their crystal structure and in solution by nuclear magnetic resonance. Evaluation of intermolecular and hydrogen bonding interactions as well as packing features, have been also carried out, evidencing interesting packing motifs. Their gas phase reactivity, as protonated and deprotonated molecules, has been investigated by electrospray ionization, high resolution and collision-induced dissociation multiple stage mass spectrometry. Deydrogenation reactions have been observed as a function of the capillary voltage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1477-0539
pubmed:author
pubmed:issnType
Electronic
pubmed:day
7
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5339-44
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Synthesis, structural and conformational properties, and gas phase reactivity of 1,4-dihydropyridine ester and ketone derivatives.
pubmed:affiliation
Dipartimento di Chimica, Università di Siena, via Aldo Moro, 53100, Siena, Italy. gianluca.giorgi@unisi.it
pubmed:publicationType
Journal Article