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pubmed-article:20875415pubmed:abstractTextAn important component of enteric inhibitory neurotransmission is mediated by a purine neurotransmitter, such as adenosine 5'-triphosphate (ATP), binding to P2Y1 receptors and activating small conductance K(+) channels. In murine colon ?-nicotinamide adenine dinucleotide (?-NAD) is released with ATP and mimics the pharmacology of inhibitory neurotransmission better than ATP. Here ?-NAD and ATP were compared as possible inhibitory neurotransmitters in human and monkey colons.lld:pubmed
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pubmed-article:20875415pubmed:authorpubmed-author:KohSang DonSDlld:pubmed
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pubmed-article:20875415pubmed:copyrightInfoCopyright © 2011. Published by Elsevier Inc.lld:pubmed
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pubmed-article:20875415pubmed:articleTitle?-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons.lld:pubmed
pubmed-article:20875415pubmed:affiliationDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557-0352, USA.lld:pubmed
pubmed-article:20875415pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20875415pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed
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