rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-10-19
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pubmed:abstractText |
Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas. To elucidate the mechanism of hyaluronan accumulation, we examined the expression levels of the hyaluronan synthases (HAS1, HAS2 and HAS3) and hyaluronidases (HYAL1 and HYAL2), and correlated them with hyaluronan content and HAS1-3 immunoreactivity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/GPI-Linked Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glucuronosyltransferase,
http://linkedlifedata.com/resource/pubmed/chemical/HAS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/HAS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/HAS3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hyal2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hyaluronoglucosaminidase
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
512
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pubmed:meshHeading |
pubmed-meshheading:20875124-Adult,
pubmed-meshheading:20875124-Aged,
pubmed-meshheading:20875124-Aged, 80 and over,
pubmed-meshheading:20875124-Carcinoma, Endometrioid,
pubmed-meshheading:20875124-Cell Adhesion Molecules,
pubmed-meshheading:20875124-Endometrial Neoplasms,
pubmed-meshheading:20875124-Female,
pubmed-meshheading:20875124-GPI-Linked Proteins,
pubmed-meshheading:20875124-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20875124-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20875124-Glucuronosyltransferase,
pubmed-meshheading:20875124-Humans,
pubmed-meshheading:20875124-Hyaluronoglucosaminidase,
pubmed-meshheading:20875124-Middle Aged
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pubmed:year |
2010
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pubmed:articleTitle |
Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma.
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pubmed:affiliation |
Institute of Clinical Medicine, Department of Pathology and Forensic Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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