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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-1-3
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pubmed:abstractText |
Suppression of Kinesin-1 by antisense oligonucleotides, or overexpression of dominant-negative acting kinesin heavy chain, has been reported to affect the sustained phase of glucose-stimulated insulin secretion in ?-cells in vitro. In this study, we examined the in vivo physiological role of Kinesin-1 in ?-cell development and function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
320-30
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20870970-Amino Acid Sequence,
pubmed-meshheading:20870970-Animals,
pubmed-meshheading:20870970-Base Sequence,
pubmed-meshheading:20870970-Blotting, Western,
pubmed-meshheading:20870970-DNA Primers,
pubmed-meshheading:20870970-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20870970-Genotype,
pubmed-meshheading:20870970-Humans,
pubmed-meshheading:20870970-Insulin,
pubmed-meshheading:20870970-Insulin-Secreting Cells,
pubmed-meshheading:20870970-Islets of Langerhans,
pubmed-meshheading:20870970-Kinesin,
pubmed-meshheading:20870970-Male,
pubmed-meshheading:20870970-Mice,
pubmed-meshheading:20870970-Mice, Knockout,
pubmed-meshheading:20870970-Molecular Sequence Data,
pubmed-meshheading:20870970-Oligonucleotides, Antisense,
pubmed-meshheading:20870970-Peptide Fragments
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pubmed:year |
2011
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pubmed:articleTitle |
Targeted inactivation of kinesin-1 in pancreatic ?-cells in vivo leads to insulin secretory deficiency.
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pubmed:affiliation |
Department of Biochemistry, The University of Hong Kong, Hong Kong.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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