Source:http://linkedlifedata.com/resource/pubmed/id/20867675
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2010-9-27
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pubmed:abstractText |
When spreading onto a protein microlattice living cells spontaneously acquire simple shapes determined by the lattice geometry. This suggests that, on a lattice, living cells' shapes are in thermodynamic metastable states. Using a model at thermodynamic equilibrium we are able to reproduce the observed shapes. We build a phase diagram based on two adimensional parameters characterizing essential cellular properties involved in spreading: the cell's compressibility and fluctuations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1079-7114
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
17
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
128101
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pubmed:meshHeading |
pubmed-meshheading:20867675-Actins,
pubmed-meshheading:20867675-Biomechanics,
pubmed-meshheading:20867675-Cell Adhesion,
pubmed-meshheading:20867675-Cell Shape,
pubmed-meshheading:20867675-Compressive Strength,
pubmed-meshheading:20867675-Cytoskeleton,
pubmed-meshheading:20867675-Elasticity,
pubmed-meshheading:20867675-Extracellular Matrix Proteins,
pubmed-meshheading:20867675-Models, Biological,
pubmed-meshheading:20867675-Monte Carlo Method,
pubmed-meshheading:20867675-Thermodynamics
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pubmed:year |
2010
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pubmed:articleTitle |
Single cells spreading on a protein lattice adopt an energy minimizing shape.
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pubmed:affiliation |
Institut Néel, CNRS et Université Joseph Fourier, BP166, 38042 Grenoble Cédex 9, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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