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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-5-23
pubmed:abstractText
In order to evaluate brain stem dysfunction related to ischemic process, the authors monitored the Brainstem Auditory Evoked Responses (BAERs) with time in a brain stem ischemic model. 19 adult mongrel cats were divided into two groups: embolization (n = 14) and sham operated control (n = 5). Embolization was done by injecting cylindrical silicone embolus to the right vertebral artery. Each successful embolization of the basilar artery was then confirmed by vertebral angiography. BAERs were monitored before embolization and then 5-10 min, 15 min, 30 min, 60 min, 3 hr and 6 hr after embolization. The presence of ischemic lesion caused by embolization was confirmed by injecting 2% Evans blue solution 30 min before sacrificing the animals. Leakage of the dye was observed. In embolized animals, significant (Student t test, p less than 0.05) delay of interpeak latencies of waves 1-3, 3-5, and 1-5 was observed 15 min after embolization. This delay became more significant (p less than 0.01) 30 min after embolization. These results provide evidence for the usefulness of BAERs monitoring which can be used to complement other diagnostic methods for patients with vertebrobasilar insufficiency and/or infarction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0018-2052
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Changes of brainstem auditory evoked responses (BAERs) in a brain stem ischemic model using embolization technique in cats, a preliminary study.
pubmed:affiliation
Department of Neurosurgery, Hiroshima University School of Medicine, Japan.
pubmed:publicationType
Journal Article