Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-12-20
pubmed:abstractText
The present study compares nerve growth factor (NGF) levels between preeclamptic (PE) (n=86) and normotensive (NT) women (n=105) and their associations with blood pressure and infant size. Maternal plasma NGF levels were reduced (p<0.05) in the PE group as compared to the NT group. Furthermore, NGF levels were reduced in PE mothers delivering low birth weight babies (LBW) as compared to NT mothers delivering LBW babies. Maternal NGF levels were negatively (p=0.029) associated with blood pressure in preeclamptic mothers. Cord NGF levels were negatively associated (p=0.026) with birth weight in the normotensive group. NGF levels are differently regulated in preeclamptic and normotensive mothers delivering LBW babies. Future studies need to investigate mechanisms underlying this pathophysiology and follow-up of these babies to better understand the role of NGF in brain development in later life.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1873-474X
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 ISDN. Published by Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-5
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Nerve growth factor, birth outcome and pre-eclampsia.
pubmed:affiliation
Department of Nutritional Medicine, Interactive Research School for Health Affairs, Bharati Vidyapeeth University, Pune 411043, India.
pubmed:publicationType
Journal Article