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pubmed-article:20863523pubmed:abstractTextNeoadjuvant treatment strategies have been developed to improve survival of patients with locally advanced rectal cancer. Since mainly patients with major histopathologic response benefit from this therapy, predictive markers are needed. The gene polymorphism of the X-ray-repair-cross complementing (XRCC1-) gene (rs25487) was analyzed to predict response to neoadjuvant radiochemotherapy and prognosis in patients with locally advanced rectal cancer.lld:pubmed
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pubmed-article:20863523pubmed:copyrightInfoCopyright © 2010 Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:20863523pubmed:articleTitleXRCC1 gene polymorphism for prediction of response and prognosis in the multimodality therapy of patients with locally advanced rectal cancer.lld:pubmed
pubmed-article:20863523pubmed:affiliationDepartment of General, Visceral, and Cancer Surgery, University of Cologne, Cologne, Germany.lld:pubmed
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