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rdf:type |
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lifeskim:mentions |
umls-concept:C0007113,
umls-concept:C0009429,
umls-concept:C0030705,
umls-concept:C0033325,
umls-concept:C0205179,
umls-concept:C0678951,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1366475,
umls-concept:C1517927,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
2010-10-19
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pubmed:abstractText |
Neoadjuvant treatment strategies have been developed to improve survival of patients with locally advanced rectal cancer. Since mainly patients with major histopathologic response benefit from this therapy, predictive markers are needed. The gene polymorphism of the X-ray-repair-cross complementing (XRCC1-) gene (rs25487) was analyzed to predict response to neoadjuvant radiochemotherapy and prognosis in patients with locally advanced rectal cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1095-8673
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e61-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20863523-Chemotherapy, Adjuvant,
pubmed-meshheading:20863523-Combined Modality Therapy,
pubmed-meshheading:20863523-DNA-Binding Proteins,
pubmed-meshheading:20863523-Female,
pubmed-meshheading:20863523-Genotype,
pubmed-meshheading:20863523-Humans,
pubmed-meshheading:20863523-Kaplan-Meier Estimate,
pubmed-meshheading:20863523-Male,
pubmed-meshheading:20863523-Middle Aged,
pubmed-meshheading:20863523-Multivariate Analysis,
pubmed-meshheading:20863523-Polymorphism, Single Nucleotide,
pubmed-meshheading:20863523-Predictive Value of Tests,
pubmed-meshheading:20863523-Preoperative Care,
pubmed-meshheading:20863523-Prognosis,
pubmed-meshheading:20863523-Radiotherapy, Adjuvant,
pubmed-meshheading:20863523-Rectal Neoplasms,
pubmed-meshheading:20863523-Retrospective Studies,
pubmed-meshheading:20863523-Severity of Illness Index,
pubmed-meshheading:20863523-Tumor Markers, Biological
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pubmed:year |
2010
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pubmed:articleTitle |
XRCC1 gene polymorphism for prediction of response and prognosis in the multimodality therapy of patients with locally advanced rectal cancer.
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pubmed:affiliation |
Department of General, Visceral, and Cancer Surgery, University of Cologne, Cologne, Germany.
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pubmed:publicationType |
Journal Article
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