Linked Life Data

2086321

Source:http://linkedlifedata.com/resource/pubmed/id/2086321

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-5-23
pubmed:abstractText
Female mice were treated with 0 or 8 mg/kg chlordane daily for 18 days during pregnancy. The fetuses of these mice were assayed for fetal liver hematopoietic activity at 18 days gestational age. Hematopoietic activity was evaluated for in vitro granulocyte-macrophage colony-forming units (GM-CFU) and in vivo spleen CFU (CFU-S). The consistent finding was a significant depression of the numbers of both fetal liver GM-CFU and CFU-S without a change in liver cellularity in fetuses exposed to 8 mg/kg chlordane. These data show that the damage to stem cells that persists into adult life as a result of chlordane exposure, as reported earlier by Barnett et al. (1990) Fundam. Appl. Toxicol. 14, 688-695, occurred during the fetal period.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0272-0590
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
820-2
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Alteration of fetal liver colony formation by prenatal chlordane exposure.
pubmed:affiliation
Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock 72205.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.