Source:http://linkedlifedata.com/resource/pubmed/id/20862335
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
2010-9-23
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| pubmed:abstractText |
The interest in tissue- and cell-specific S100 proteins physiological roles in the brain remains high. However, necessary experimental data for the assessment of their dynamics in one of the most important brain activities, its plasticity, is not sufficient. We studied the expression of S100B, S100A1, and S100A6 mRNA in the subfield CA1 of rat hippocampal slices after tetanic and low-frequency stimulation by real-time PCR. Within 30?min after tetanization, a 2-4 fold increase of the S100B mRNA level was observed as compared to the control (intact slices) or to low-frequency stimulation. Subsequently, the S100B mRNA content gradually returned to baseline. The amount of S100A1 mRNA gradually increased during first hour and maintained at the achieved level in the course of second hour after tetanization. The level of S100A6 mRNA did not change following tetanization or low-frequency stimulation.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:issn |
2090-0171
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
2010
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:year |
2010
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| pubmed:articleTitle |
A Comparison of the Dynamics of S100B, S100A1, and S100A6 mRNA Expression in Hippocampal CA1 Area of Rats during Long-Term Potentiation and after Low-Frequency Stimulation.
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| pubmed:affiliation |
Institute for Molecular Biology and Biophysics, Siberian Branch of the Russian Academy of Medical Sciences, 2 Timakova Street, Novosibirsk 630117, Russia.
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| pubmed:publicationType |
Journal Article
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