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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-9-23
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pubmed:abstractText |
Pathogenic bacteria adhere to the host cell surface using a family of outer membrane proteins called Trimeric Autotransporter Adhesins (TAAs). Although TAAs are highly divergent in sequence and domain structure, they are all conceptually comprised of a C-terminal membrane anchoring domain and an N-terminal passenger domain. Passenger domains consist of a secretion sequence, a head region that facilitates binding to the host cell surface, and a stalk region.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AbendrothJanJ,
pubmed-author:BrittnacherMitch JMJ,
pubmed-author:DieterichShellie HSH,
pubmed-author:EdwardsThomas ETE,
pubmed-author:GuoWenjinW,
pubmed-author:HewittStephen NSN,
pubmed-author:KelleyAngelaA,
pubmed-author:LeiblyDavidD,
pubmed-author:MasoudiAmirA,
pubmed-author:MillerSamuel ISI,
pubmed-author:MylerPeter JPJ,
pubmed-author:PhanIsabelleI,
pubmed-author:StakerBart LBL,
pubmed-author:StewartLance JLJ,
pubmed-author:Van VoorhisWesley CWC
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:meshHeading |
pubmed-meshheading:20862217-Adhesins, Bacterial,
pubmed-meshheading:20862217-Amino Acid Sequence,
pubmed-meshheading:20862217-Bacterial Outer Membrane Proteins,
pubmed-meshheading:20862217-Burkholderia pseudomallei,
pubmed-meshheading:20862217-Crystallography, X-Ray,
pubmed-meshheading:20862217-Humans,
pubmed-meshheading:20862217-Melioidosis,
pubmed-meshheading:20862217-Molecular Conformation,
pubmed-meshheading:20862217-Molecular Sequence Data,
pubmed-meshheading:20862217-Protein Multimerization,
pubmed-meshheading:20862217-Protein Structure, Tertiary
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pubmed:year |
2010
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pubmed:articleTitle |
Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head.
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pubmed:affiliation |
Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, USA. tedwards@embios.com
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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