Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1991-5-23
|
pubmed:abstractText |
Thirty hospitalized patients (23 men and 7 women), aged 42 to 78 years, with impaired host defences for malignant underlying diseases and affected by life-threatening infections, were treated with the imipenem/cilastatin combination at a dosage ranging between 2 and 4 g daily i.v. at 8 or 12 h intervals. The average length of therapy was 9.6 +/- 2.09 days. The isolated organisms were as follows: Pseudomonas aeruginosa [12], Escherichia coli [10], Klebsiella pneumoniae [5], Proteus mirabilis [3], P. vulgaris [2], Serratia marcescens [1], Staphylococcus aureus [3], Streptococcus faecalis [3], Bacteroides fragilis [5]. In fourteen patients a mixed infection was observed. Twenty-three patients (76.66%) were completely cured of infection and 35 out of 44 isolated organisms (79.54%) were eradicated. No important side-effects were observed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0378-6501
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
293-7
|
pubmed:dateRevised |
2005-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2086164-Adult,
pubmed-meshheading:2086164-Aged,
pubmed-meshheading:2086164-Bacteria,
pubmed-meshheading:2086164-Bacterial Infections,
pubmed-meshheading:2086164-Cilastatin,
pubmed-meshheading:2086164-Drug Therapy, Combination,
pubmed-meshheading:2086164-Female,
pubmed-meshheading:2086164-Humans,
pubmed-meshheading:2086164-Imipenem,
pubmed-meshheading:2086164-Male,
pubmed-meshheading:2086164-Middle Aged,
pubmed-meshheading:2086164-Neoplasms
|
pubmed:year |
1990
|
pubmed:articleTitle |
Clinical evaluation of the imipenem/cilastatin combination in the therapy of severe infections in patients with malignant diseases.
|
pubmed:affiliation |
Institute of Internal Medicine, 1st Medical School, University of Naples, Italy.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|