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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-2-21
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pubmed:abstractText |
Chronic hypersensitivity pneumonitis (HP) can lead to irreversible pulmonary fibrosis. A good animal model is essential to elucidate the mechanisms of this disease. We previously reported that a Th2 predominance may play an important role in the fibrogenesis in chronic HP patients. A study was undertaken to evaluate whether Th2-biased immune responses were crucial during the processes of lung fibrosis in a murine model of chronic HP.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0097
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
154
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
264-74
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pubmed:meshHeading |
pubmed-meshheading:20861649-Alveolitis, Extrinsic Allergic,
pubmed-meshheading:20861649-Animals,
pubmed-meshheading:20861649-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:20861649-Chronic Disease,
pubmed-meshheading:20861649-Cytokines,
pubmed-meshheading:20861649-Disease Models, Animal,
pubmed-meshheading:20861649-Female,
pubmed-meshheading:20861649-Humans,
pubmed-meshheading:20861649-Immunohistochemistry,
pubmed-meshheading:20861649-Lung,
pubmed-meshheading:20861649-Mice,
pubmed-meshheading:20861649-Mice, Inbred BALB C,
pubmed-meshheading:20861649-Mice, Inbred C57BL,
pubmed-meshheading:20861649-Mice, Inbred Strains,
pubmed-meshheading:20861649-Pulmonary Fibrosis,
pubmed-meshheading:20861649-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20861649-Species Specificity,
pubmed-meshheading:20861649-Th2 Cells
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pubmed:year |
2011
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pubmed:articleTitle |
Th2-biased immune responses are important in a murine model of chronic hypersensitivity pneumonitis.
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pubmed:affiliation |
Department of Integrated Pulmonology, Tokyo Medical and Dental University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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