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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1991-5-23
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pubmed:abstractText |
A clinical trial comparing 5 days' treatment with amoxycillin/clavulanate (group A) and a single dose of fosfomycin trometamol (group B) is presented. The study was done in symptomatic patients presenting to their family practitioner, with the microbiological testing being carried out in a university hospital laboratory. Of 62 patients with significant bacteriuria, 29 were given amoxycillin/clavulanate and 33 fosfomycin trometamol, in a randomized fashion. Cure rates 1 week and 5 weeks after the end of treatment were 72 and 65% in group A and 85 and 81% in group B. Adverse events assessed in 141 patients were unusual (10.1% in group A and 8.3% in group B) and were mild in nature. The results of this study suggest that single-dose treatment with fosfomycin trometamol is effective and acceptable as a conventional course of amoxycillin clavulanate for the treatment of simple acute dysuria and/or frequency with infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0009-3157
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
24-6
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:2085984-Acute Disease,
pubmed-meshheading:2085984-Amoxicillin,
pubmed-meshheading:2085984-Amoxicillin-Potassium Clavulanate Combination,
pubmed-meshheading:2085984-Bacteriuria,
pubmed-meshheading:2085984-Clavulanic Acids,
pubmed-meshheading:2085984-Drug Therapy, Combination,
pubmed-meshheading:2085984-Family Practice,
pubmed-meshheading:2085984-Female,
pubmed-meshheading:2085984-Fosfomycin,
pubmed-meshheading:2085984-Humans,
pubmed-meshheading:2085984-Male,
pubmed-meshheading:2085984-Remission Induction,
pubmed-meshheading:2085984-Time Factors,
pubmed-meshheading:2085984-Urinary Tract Infections
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pubmed:year |
1990
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pubmed:articleTitle |
General practitioner study: fosfomycin trometamol versus amoxycillin clavulanate in acute urinary tract infections.
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pubmed:affiliation |
Earnswood Medical Centre, Crewe, London, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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